Versatile amine-promoted mild methanolysis of 3,5-dinitrobenzoates and its application to the synthesis of Colorado potato beetle pheromone.

Yamano Y, Sasaki H, Wada A. Chem Pharm Bull. 2017;65(10):940-944. doi: 10.1248/cpb.c17-00462.

A mild deacylation method for 3,5-dinitrobenzoates using methanolic solutions of amines, such as dialkylamines, was developed. The method's versatility was confirmed by applying it to synthesizing a key intermediate for Colorado potato beetle pheromone.